Terlipressin Injection
- Packing: 10 Ml Ampoule.
- Available Strength : 100 Mcg/Ml
Description
Product Description: Terlipressin Injection is a meticulously formulated pharmaceutical solution designed to manage various conditions related to vasodilatory shock and gastrointestinal bleeding. It contains terlipressin, a synthetic analogue of vasopressin, known for its vasoconstrictive and hemostatic effects. Manufactured to the highest quality standards, this injection offers targeted therapy for conditions such as hepatorenal syndrome and acute variceal bleeding.
Indications and Usage: Terlipressin Injection is indicated for the management of hepatorenal syndrome, a severe complication of liver cirrhosis characterized by renal dysfunction and refractory ascites. It is also used for the treatment of acute variceal bleeding, a life-threatening complication of portal hypertension. Additionally, it may be employed in the management of other conditions associated with vasodilatory shock.
Dosage and Administration: The dosage of Terlipressin Injection varies depending on the specific indication, the severity of the condition, and individual patient response. It is typically administered via intravenous infusion under the supervision of a qualified healthcare professional. The dosage regimen may involve initial loading doses followed by maintenance infusions, as determined by the treating physician.
Dosage Forms and Strengths: Terlipressin Injection is available as a sterile solution in vials containing specific concentrations of terlipressin formulated for parenteral administration. Each vial is carefully manufactured to ensure accurate dosing and optimal therapeutic outcomes.
Contraindications: This product is contraindicated in patients with a known hypersensitivity to terlipressin or any of the excipients. It should not be used in patients with myocardial infarction, ventricular tachycardia, or severe hypertension. Additionally, it is contraindicated in pregnant women, particularly during the first trimester.
Warnings and Precautions: Healthcare providers should exercise caution when prescribing Terlipressin Injection to patients with a history of cardiovascular disease or renal impairment. Rarely, serious adverse effects such as myocardial ischemia, arrhythmias, or water intoxication may occur. Patients should be monitored closely for signs of these adverse effects during therapy.
Adverse Reactions/Side Effects: Common adverse reactions associated with Terlipressin Injection include nausea, vomiting, and abdominal discomfort. Rarely, serious adverse effects such as hypertension, bradycardia, or hyponatremia may occur. Patients should be advised to report any unusual symptoms promptly.
Drug Interactions: Concomitant use of Terlipressin Injection with other drugs that affect cardiovascular function or electrolyte balance may potentiate the effects of terlipressin or alter its pharmacokinetics. Healthcare providers should review the patient's medication profile carefully to avoid potential drug interactions.
Use In Specific Populations Description: Safety and efficacy of Terlipressin Injection in pediatric patients, pregnant women, and nursing mothers have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Terlipressin Injection is supplied as a sterile solution in vials for parenteral administration. It should be stored at controlled room temperature away from light and moisture. Care should be taken to avoid freezing or excessive heat exposure. Unused portions should be discarded according to standard procedures for biohazardous waste.