Sulbutamol Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 500 Mcg/Ml
Description
Product Description: Sulbutamol Injection is a sterile solution containing the active ingredient sulbutamol, which belongs to the class of medications known as beta-2 adrenergic agonists. It is used for the management of bronchospasm associated with conditions such as asthma, chronic obstructive pulmonary disease (COPD), and other respiratory disorders.
Indications and Usage: Sulbutamol Injection is indicated for the treatment of bronchospasm in patients with reversible obstructive airway diseases, including asthma and COPD. It is used to provide rapid relief of bronchospasm, improve airflow, and alleviate symptoms such as wheezing, shortness of breath, and chest tightness.
Dosage and Administration: The dosage of Sulbutamol Injection varies depending on the patient's age, weight, and the severity of bronchospasm. It is administered by intravenous or intramuscular injection, typically at a dose of 0.25 to 0.5 mg (0.5 to 1 mL) repeated every 4 to 6 hours as needed. The maximum recommended daily dose is 10 mg.
Dosage Forms and Strengths: Sulbutamol Injection is available as a sterile solution in vials or ampules for intravenous or intramuscular administration. Each milliliter of the solution typically contains a specified amount of sulbutamol, typically expressed in milligrams per milliliter (mg/mL).
Contraindications: Sulbutamol Injection is contraindicated in patients with a known hypersensitivity to sulbutamol or any component of the formulation. It should not be used in patients with a history of severe cardiac arrhythmias, including tachyarrhythmias or ventricular fibrillation.
Warnings and Precautions: Use caution when administering Sulbutamol Injection to patients with underlying cardiovascular disorders, hypertension, hyperthyroidism, or diabetes mellitus. Prolonged use or excessive doses may increase the risk of adverse cardiovascular effects, including tachycardia, palpitations, and myocardial ischemia. Monitor patients closely for signs of worsening symptoms or adverse reactions during treatment.
Adverse Reactions/Side Effects: Common adverse reactions associated with Sulbutamol Injection may include tremor, headache, dizziness, palpitations, tachycardia, hypokalemia, and hyperglycemia. Rare but serious adverse reactions may include paradoxical bronchospasm, cardiac arrhythmias, and allergic reactions such as rash or angioedema.
Drug Interactions: Sulbutamol Injection may interact with certain medications, including beta-blockers, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and other sympathomimetic agents. Concurrent use may potentiate or antagonize the effects of sulbutamol, leading to increased or decreased bronchodilation. Adjust the dosage of concomitant medications as necessary and monitor patients closely for signs of drug interactions.
Use In Specific Populations Description: Safety and efficacy of Sulbutamol Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Sulbutamol Injection is supplied as a sterile solution in vials or ampules for intravenous or intramuscular administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.