Sodium Bicarbonate Injection
- Packing: 10 ml, 25 ml , 1 ml, 2 ml, 20 ml Ampoule.
- Available Strength : 8.4 % W/V
Description
Product Description: Sodium Bicarbonate Injection is a sterile, non-pyrogenic solution containing sodium bicarbonate, a buffering agent essential for maintaining acid-base balance in the body. It is formulated for intravenous administration to correct metabolic acidosis and manage other conditions requiring bicarbonate therapy. Manufactured to the highest quality standards, Sodium Bicarbonate Injection offers vital support for restoring normal pH levels and optimizing physiological function.
Indications and Usage: Sodium Bicarbonate Injection is indicated for the treatment of metabolic acidosis associated with conditions such as renal failure, diabetic ketoacidosis, and severe dehydration. It is also used to manage certain drug toxicities, including tricyclic antidepressant overdose and salicylate poisoning. Additionally, it may be used as an alkalizing agent in the management of certain urinary tract conditions.
Dosage and Administration: The dosage of Sodium Bicarbonate Injection varies depending on the patient's acid-base status, clinical condition, and response to therapy. It is typically administered via intravenous infusion under the supervision of a healthcare professional. The recommended dosage regimen should be individualized based on the patient's pH level, serum bicarbonate concentration, and underlying etiology of acidosis.
Dosage Forms and Strengths: Sodium Bicarbonate Injection is available as a sterile solution in vials or ampules containing specific concentrations of sodium bicarbonate formulated for intravenous administration. Each container is meticulously labeled with the sodium bicarbonate concentration to ensure accurate dosing and optimal therapeutic outcomes.
Contraindications: This product is contraindicated in patients with metabolic alkalosis, hypocalcemia, hypernatremia, or severe heart failure. It should not be used in patients with severe renal impairment or respiratory alkalosis. Additionally, caution should be exercised in patients with fluid overload or edema, as sodium bicarbonate may exacerbate these conditions.
Warnings and Precautions: Healthcare providers should exercise caution when administering Sodium Bicarbonate Injection to patients with impaired renal function, as excessive bicarbonate supplementation may lead to metabolic alkalosis and hypernatremia. Electrolyte levels, including sodium and bicarbonate, should be monitored regularly during therapy. Intravenous infusion of sodium bicarbonate should be administered slowly and diluted appropriately to minimize the risk of infusion-related adverse reactions.
Adverse Reactions/Side Effects: Common adverse reactions associated with Sodium Bicarbonate Injection include local irritation at the injection site, nausea, vomiting, and headache. Excessive bicarbonate supplementation may cause metabolic alkalosis, hypernatremia, and fluid overload. Patients should be monitored closely for signs of electrolyte imbalances and metabolic disturbances.
Drug Interactions: Sodium Bicarbonate Injection may interact with certain medications, including corticosteroids, diuretics, and medications containing calcium or magnesium. Healthcare providers should review the patient's medication profile carefully to identify potential drug interactions and adjust dosage as necessary to minimize risks.
Use In Specific Populations Description: Safety and efficacy of Sodium Bicarbonate Injection in pediatric patients, pregnant women, and nursing mothers have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Sodium Bicarbonate Injection is supplied as a sterile solution in vials or ampules for intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.