Progesterone Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 25 Mg/Ml
Description
Product Description: Progesterone Injection is a pharmaceutical formulation containing progesterone, a natural female hormone essential for various reproductive functions. It is indicated for the treatment of infertility, amenorrhea, and certain hormonal imbalances. This injection provides a convenient and effective way to administer progesterone for therapeutic purposes.
Indications and Usage: Progesterone Injection is indicated for the treatment of infertility due to luteal phase deficiency, amenorrhea, and certain hormonal imbalances. It is used to support early pregnancy in women undergoing assisted reproductive techniques such as in vitro fertilization (IVF) or embryo transfer. Additionally, it may be used as part of hormone replacement therapy in postmenopausal women.
Dosage and Administration: The dosage of Progesterone Injection varies depending on the patient's condition, age, weight, and response to therapy. It is administered via intramuscular injection under the supervision of a healthcare professional. The injection site should be rotated to minimize the risk of local tissue irritation. The dosage regimen should be individualized based on the patient's clinical response and any underlying medical conditions.
Dosage Forms and Strengths: Progesterone Injection is available as a sterile solution in single-dose vials. Each mL of solution contains progesterone equivalent to 50 mg or 100 mg of progesterone.
Contraindications: Progesterone Injection is contraindicated in patients with known or suspected pregnancy, active thrombophlebitis or thromboembolic disorders, undiagnosed vaginal bleeding, or hypersensitivity to progesterone or any of the excipients. It should not be used in patients with a history of breast cancer or other hormone-sensitive malignancies.
Warnings and Precautions: Administration of Progesterone Injection requires careful monitoring of the patient's clinical response and any signs of adverse effects. It should be used with caution in patients with a history of depression or other psychiatric disorders, as it may exacerbate these conditions. Long-term use may be associated with a loss of bone mineral density; therefore, periodic evaluation of bone health is recommended.
Adverse Reactions/Side Effects: Common adverse reactions associated with Progesterone Injection include injection site reactions, such as pain, swelling, or redness. Rare but serious adverse reactions may include thromboembolic events, such as deep vein thrombosis or pulmonary embolism, or allergic reactions such as rash or pruritus. If any adverse reactions occur, the injection should be discontinued, and appropriate medical treatment initiated.
Drug Interactions: Progesterone Injection may interact with other medications that affect hormonal balance or liver metabolism, such as anticonvulsants, corticosteroids, or certain antiretroviral drugs. Concurrent use with hormonal contraceptives may alter the effectiveness of both medications. Close monitoring is recommended when administering progesterone with other drugs affecting the coagulation cascade or liver function.
Use In Specific Populations Description: The safety and efficacy of Progesterone Injection in pediatric patients, geriatric patients, and pregnant or lactating women have not been established. Use with caution in these populations, and only if the potential benefits outweigh the risks. Close monitoring is recommended in patients with renal or hepatic impairment.
How Supplied/Storage and Handling: Progesterone Injection is supplied as a sterile solution in single-dose vials. It should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F), protected from light and moisture. Do not freeze. Discard any unused portion of the solution.