Oestradiol Benzoate Injection

Oestradiol Benzoate Injection

  • Packing: 2 Ml Vial
  • Available Strength : 1 Mg/Ml

Description

Product Description: Oestradiol Benzoate Injection is a hormonal medication containing estradiol benzoate, a synthetic form of the hormone estradiol. It is formulated for injection and is used for various therapeutic and reproductive health purposes.

Indications and Usage: Oestradiol Benzoate Injection is indicated for hormone replacement therapy (HRT) in women with menopausal symptoms, such as hot flashes, vaginal dryness, and mood changes. It may also be used in assisted reproductive technology (ART) procedures, including in vitro fertilization (IVF), to support follicle development.

Dosage and Administration: The dosage of Oestradiol Benzoate Injection varies depending on the indication and individual patient factors. It is typically administered via intramuscular injection according to a prescribed dosing schedule determined by a healthcare provider.

Dosage Forms and Strengths: Oestradiol Benzoate Injection is available as a sterile solution in vials or ampules. Each milliliter of solution contains a specific amount of estradiol benzoate, typically ranging from 1 mg/mL to 10 mg/mL.

Contraindications: Oestradiol Benzoate Injection is contraindicated in pregnant women, women with a history of breast cancer, estrogen-sensitive tumors, thromboembolic disorders, and liver dysfunction. It should not be used in individuals with hypersensitivity to estradiol or any of the components of the formulation.

Warnings and Precautions: Before initiating therapy with Oestradiol Benzoate Injection, healthcare providers should evaluate patients for cardiovascular risk factors, including hypertension, diabetes, and smoking. Patients should be monitored regularly for signs of thromboembolic events, breast abnormalities, and other adverse effects associated with estrogen therapy.

Adverse Reactions/Side Effects: Common adverse reactions associated with Oestradiol Benzoate Injection include breast tenderness, vaginal bleeding, nausea, bloating, and mood changes. Other potential side effects may include headaches, fluid retention, and allergic reactions.

Drug Interactions: Oestradiol Benzoate Injection may interact with other medications, including anticoagulants, corticosteroids, anticonvulsants, and herbal supplements. Healthcare providers should carefully evaluate patients for potential drug interactions before initiating therapy.

Use In Specific Populations Description: Oestradiol Benzoate Injection is not recommended for use in pregnant women or women who are breastfeeding. It should be used with caution in women with a history of cardiovascular disease, liver dysfunction, or other medical conditions that may increase the risk of adverse effects.

How Supplied/Storage and Handling: Oestradiol Benzoate Injection is supplied as a sterile solution in vials or ampules. It should be stored at controlled room temperature, protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.