Octreotide Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 50 Mcg/Ml, 100 Mcg/Ml
Description
Product Description: Octreotide Injection is a meticulously formulated pharmaceutical solution designed to manage various hormonal and neoplastic disorders. It contains octreotide acetate, a synthetic analogue of somatostatin, known for its inhibitory effects on hormone secretion and tumor growth. Manufactured to the highest quality standards, this injection offers targeted therapy for conditions such as acromegaly, carcinoid syndrome, and gastroenteropancreatic neuroendocrine tumors.
Indications and Usage: Octreotide Injection is indicated for the treatment of acromegaly, a hormonal disorder characterized by excessive growth hormone production. It is also used to alleviate symptoms of carcinoid syndrome, such as flushing and diarrhea, and to inhibit tumor growth in gastroenteropancreatic neuroendocrine tumors. Additionally, it is employed for the management of variceal bleeding in patients with portal hypertension.
Dosage and Administration: The dosage of Octreotide Injection varies depending on the specific indication, the severity of the condition, and individual patient response. It is typically administered via subcutaneous or intravenous route under the supervision of a qualified healthcare professional. The dosage regimen may involve initial loading doses followed by maintenance injections, as determined by the treating physician.
Dosage Forms and Strengths: Octreotide Injection is available as a sterile solution in vials containing specific concentrations of octreotide acetate formulated for parenteral administration. Each vial is carefully manufactured to ensure accurate dosing and optimal therapeutic outcomes.
Contraindications: This product is contraindicated in patients with a known hypersensitivity to octreotide acetate or any of the excipients. It should not be used in patients with untreated diabetes mellitus, cholelithiasis, or severe gastrointestinal motility disorders. Additionally, it is contraindicated in pregnant women, particularly during the first trimester.
Warnings and Precautions: Healthcare providers should exercise caution when prescribing Octreotide Injection to patients with a history of gallbladder disease, renal impairment, or thyroid dysfunction. Rarely, serious adverse effects such as bradycardia, hyperglycemia, or hypothyroidism may occur. Patients should be monitored closely for signs of these adverse effects during therapy.
Adverse Reactions/Side Effects: Common adverse reactions associated with Octreotide Injection include injection site reactions, gastrointestinal disturbances, and alterations in glucose metabolism. Rarely, serious adverse effects such as cardiac arrhythmias, pancreatitis, or allergic reactions may occur. Patients should be advised to report any unusual symptoms promptly.
Drug Interactions: Concomitant use of Octreotide Injection with other drugs that affect heart rate, glucose metabolism, or gastrointestinal motility may potentiate the effects of octreotide or alter its pharmacokinetics. Healthcare providers should review the patient's medication profile carefully to avoid potential drug interactions.
Use In Specific Populations Description: Safety and efficacy of Octreotide Injection in pediatric patients, pregnant women, and nursing mothers have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Octreotide Injection is supplied as a sterile solution in vials for parenteral administration. It should be stored at controlled room temperature away from light and moisture. Care should be taken to avoid freezing or excessive heat exposure. Unused portions should be discarded according to standard procedures for biohazardous waste.