Metoclopramide Injection
- Packing: 2 Ml Ampoule.
- Available Strength : 5 Mg/Ml
Description
Product Description: Our Metoclopramide Injection is a meticulously formulated pharmaceutical solution designed to alleviate symptoms of gastrointestinal disorders effectively. It contains metoclopramide, a dopamine receptor antagonist with prokinetic and antiemetic properties. Manufactured to the highest quality standards, this injection is trusted by healthcare professionals for its reliability and efficacy in managing nausea, vomiting, and gastroparesis.
Indications and Usage: Metoclopramide Injection is indicated for the treatment of nausea and vomiting associated with various gastrointestinal conditions, including chemotherapy-induced nausea and vomiting, postoperative nausea and vomiting, and diabetic gastroparesis. Additionally, it is used off-label for the management of gastroesophageal reflux disease (GERD) and functional dyspepsia.
Dosage and Administration: The dosage of Metoclopramide Injection varies depending on the patient's age, weight, and clinical condition. It is typically administered via intravenous or intramuscular route under the supervision of a qualified healthcare professional. Dosage adjustments may be necessary based on the patient's response to therapy and individual tolerance.
Dosage Forms and Strengths: Metoclopramide Injection is available as a sterile solution in vials containing specific concentrations of metoclopramide formulated for parenteral administration. Each vial is carefully manufactured to ensure accurate dosing and optimal therapeutic outcomes.
Contraindications: This product is contraindicated in patients with a known hypersensitivity to metoclopramide or any of the excipients. It should not be used in patients with gastrointestinal obstruction, perforation, or hemorrhage. Additionally, it is contraindicated in patients with pheochromocytoma or history of seizures.
Warnings and Precautions: Healthcare providers should exercise caution when prescribing Metoclopramide Injection to patients with a history of extrapyramidal symptoms, Parkinson's disease, or renal impairment. Prolonged use may lead to the development of tardive dyskinesia or neuroleptic malignant syndrome. Patients should be monitored closely for signs of these adverse effects during therapy.
Adverse Reactions/Side Effects: Common adverse reactions associated with Metoclopramide Injection include drowsiness, restlessness, fatigue, and extrapyramidal symptoms such as dystonia and akathisia. Rarely, serious adverse effects such as tardive dyskinesia, neuroleptic malignant syndrome, and hyperprolactinemia may occur. Patients should be advised to report any unusual symptoms promptly.
Drug Interactions: Concomitant use of Metoclopramide Injection with other drugs that affect dopamine receptor function or prolong the QT interval may increase the risk of adverse effects or alter the pharmacokinetics of metoclopramide. Healthcare providers should review the patient's medication profile carefully to avoid potential drug interactions.
Use In Specific Populations Description: Safety and efficacy of Metoclopramide Injection in pediatric patients, pregnant women, and nursing mothers have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Metoclopramide Injection is supplied as a sterile solution in vials for parenteral administration. It should be stored at controlled room temperature away from light and moisture. Care should be taken to avoid freezing or excessive heat exposure. Unused portions should be discarded according to standard procedures for biohazardous waste.