Methylprednisolone Sod. Succinate Injection
- Packing: Vial
- Available Strength : 40 mg, 125 mg, 500 mg, 1 gm
Description
Product Description: Methylprednisolone Sodium Succinate Injection is a sterile solution containing methylprednisolone sodium succinate, a synthetic glucocorticoid. It is formulated for intravenous or intramuscular administration and is commonly used for its anti-inflammatory and immunosuppressive properties.
Indications and Usage: Methylprednisolone Sodium Succinate Injection is indicated for the treatment of various conditions requiring corticosteroid therapy, including allergic reactions, asthma exacerbations, rheumatic disorders, dermatologic conditions, and certain hematologic disorders.
Dosage and Administration: The dosage of Methylprednisolone Sodium Succinate Injection depends on the specific condition being treated, its severity, and the patient's response to therapy. It is typically administered intravenously or intramuscularly, with dosages ranging from 40 mg to 500 mg per day in divided doses.
Dosage Forms and Strengths: Methylprednisolone Sodium Succinate Injection is available as a sterile solution in vials or ampules. The concentration of methylprednisolone sodium succinate in the solution is typically 40 mg/mL or 125 mg/mL.
Contraindications: Methylprednisolone Sodium Succinate Injection is contraindicated in patients with systemic fungal infections and in those with known hypersensitivity to corticosteroids or any component of the formulation. It should not be administered intrathecally.
Warnings and Precautions: Before initiating treatment with Methylprednisolone Sodium Succinate Injection, healthcare providers should assess patients for contraindications, including systemic infections, peptic ulcer disease, and diabetes mellitus. Prolonged use may increase the risk of osteoporosis, adrenal suppression, and opportunistic infections.
Adverse Reactions/Side Effects: Common adverse reactions associated with Methylprednisolone Sodium Succinate Injection include fluid retention, hypertension, hyperglycemia, and gastrointestinal disturbances. Other potential side effects may include immunosuppression, psychiatric reactions, and dermatologic reactions.
Drug Interactions: Methylprednisolone Sodium Succinate Injection may interact with certain medications, including anticoagulants, antidiabetic agents, and immunosuppressants. Concomitant use with other corticosteroids may increase the risk of adrenal suppression.
Use In Specific Populations Description: Methylprednisolone Sodium Succinate Injection is generally considered safe for use in pregnant and lactating women when the potential benefits outweigh the risks. Caution should be exercised in pediatric patients, as corticosteroid therapy may affect growth and development.
How Supplied/Storage and Handling: Methylprednisolone Sodium Succinate Injection is supplied as a sterile solution in vials or ampules. It should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F), protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.
