Medroxyprogesterone Acetate Tablets

Description

Medroxyprogesterone Acetate Tablet Manufacturer and Supplier in India

If you want Medroxyprogesterone Acetate Tablets for your health issue or for your pharma company, Montage Laboratories PVT. LTD, a well-known Medroxyprogesterone Acetate tablet manufacturer and supplier in Indiacan fulfill your needs. This tablet is a synthetic progestin hormone medication that contains Medroxyprogesterone Acetate (MPA), Lactose Monohydrate, Magnesium Stearate, Methylcellulose, Pregelatinized starch, and Sodium Lauryl Sulfate ingredients. It comes in oral dosage in hard form and treats menstrual disorders, endometriosis, abnormal uterine bleeding, and also used for hormone replacement therapy. You can get this tablet in 10 mg dose from this Medroxyprogesterone Acetate tablet manufacturer in India. If you are looking for a leading Medroxyprogesterone Acetate tablet supplier who offers this tablet at affordable rates and provide online delivery service, you must contact Montage Laboratories.

Montage Laboratories PVT. LTD.- Leading Medroxyprogesterone Acetate Tablet Exporter in India

Get bulk supply of Medroxyprogesterone Acetate tablet at best price for your pharma business from Montage Laboratories, the top-most Medroxyprogesterone Acetate tablet exporter in India. As a top Medroxyprogesterone exporter, we are ready to do all-India export service and provide fastest delivery service. You can collect it in bulk quantity from us. Contact us for further details of our products or services.

Product Description

Medroxyprogesterone Acetate Tablets contain medroxyprogesterone acetate, a synthetic progestin hormone. It is used to treat various conditions related to hormone imbalances, including menstrual disorders, endometriosis, and as part of hormone replacement therapy. These tablets offer a convenient oral dosage form for managing symptoms and conditions that require progestin therapy.

Indications and Usage

• Menstrual Disorders: Indicated for the treatment of secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer.
• Endometriosis: Used for the management of endometriosis-associated pain.
• Hormone Replacement Therapy: Utilized as an adjunct to estrogen therapy to prevent endometrial hyperplasia in postmenopausal women receiving estrogen.

Dosage and Administration

• Secondary Amenorrhea: 5 to 10 mg of Medroxyprogesterone Acetate Tablets once daily for 5 to 10 days.
• Abnormal Uterine Bleeding: 5 to 10 mg once daily for 5 to 10 days, beginning on day 16 or 21 of the menstrual cycle.
• Endometriosis: 10 mg three times daily for 90 consecutive days starting on the first day of the menstrual cycle.
• Hormone Replacement Therapy: 5 to 10 mg daily for 12 to 14 consecutive days per month in conjunction with estrogen therapy.

Note: Dosage should be individualized based on the patient’s response and specific medical condition. Tablets should be taken at the same time each day with or without food. Missed doses should be taken as soon as remembered, but not close to the next scheduled dose.

Dosage Forms and Strengths

Medroxyprogesterone Acetate Tablets are available in the following strengths:

• 2.5 mg
• 5 mg
• 10 mg

Contraindications

Medroxyprogesterone Acetate Tablets are contraindicated in patients with:

• Known or suspected pregnancy
• Active or history of thromboembolic disorders
• Undiagnosed abnormal genital bleeding
• Known or suspected breast cancer
• Hypersensitivity to medroxyprogesterone acetate or any component of the formulation
• Liver dysfunction or disease

Warnings and Precautions

• Cardiovascular Risk: Use with caution in patients with a history of cardiovascular disease, as medroxyprogesterone may increase the risk of thromboembolic events.
• Breast Cancer: The use of progestins in hormone replacement therapy has been associated with an increased risk of breast cancer.
• Bone Mineral Density: Long-term use may result in decreased bone mineral density; monitor bone health periodically.
• Liver Function: Use cautiously in patients with hepatic impairment.
• Mental Health: Monitor for depressive symptoms; discontinue if depression worsens.

Adverse Reactions/Side Effects

Common adverse reactions include:

• Nausea
• Weight changes
• Headache
• Breast tenderness
• Irregular menstrual periods or breakthrough bleeding
• Bloating

Serious but rare adverse effects include:

• Thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism)
• Stroke or myocardial infarction
• Visual disturbances
• Severe allergic reactions

Drug Interactions

• CYP3A4 Inducers/Inhibitors: Drugs that affect CYP3A4 (e.g., rifampin, ketoconazole) can alter medroxyprogesterone metabolism, necessitating dosage adjustments.
• Anticoagulants: Concomitant use with anticoagulants may alter the anticoagulant effect.
• Antidiabetic Agents: Monitor blood glucose levels as medroxyprogesterone may affect glucose tolerance.

Use In Specific Populations

• Pregnancy: Contraindicated in pregnancy.
• Lactation: Medroxyprogesterone is excreted in breast milk; exercise caution if administering to nursing mothers.
• Pediatric Use: Safety and effectiveness in pediatric patients have not been established.
• Geriatric Use: Dosage should be cautious, usually starting at the lower end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function.

How Supplied/Storage and Handling

Medroxyprogesterone Acetate Tablets are supplied as:

• Blister packs or bottles: Containing tablets of 2.5 mg, 5 mg, or 10 mg strengths.

Storage:

• Store at controlled room temperature between 20°C to 25°C (68°F to 77°F).
• Protect from light and moisture.
• Keep out of reach of children.

Handling:

• Tablets should be handled with dry hands and stored in their original packaging until use.
• Do not use if the packaging is damaged or if the tablets show signs of discoloration or deterioration.