Isoxsuprine Injection
- Packing: 2 Ml Ampoule.
- Available Strength : 5 Mg/Ml
Description
Product Description: Isoxsuprine Injection is a sterile solution used for intravenous administration. It belongs to the class of medications known as vasodilators and is primarily used to improve blood flow to certain parts of the body. This medication is commonly employed in the treatment of conditions such as peripheral vascular diseases, Raynaud's syndrome, and certain obstetric complications.
Indications and Usage: Isoxsuprine Injection is indicated for the treatment of peripheral vascular diseases, including arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease), and Raynaud's syndrome. Additionally, it is used to improve uterine blood flow and reduce the incidence of premature labor.
Dosage and Administration: The dosage of Isoxsuprine Injection varies depending on the indication and patient's response to therapy. For peripheral vascular diseases, the usual adult dose is 5 to 10 mg administered intravenously over 20 to 30 minutes, repeated every 6 hours as needed. In obstetric use, the recommended dose is 10 to 20 mg administered intravenously, with the option for subsequent intermittent doses or continuous infusion as determined by the healthcare provider.
Dosage Forms and Strengths: Isoxsuprine Injection is available as a sterile solution in vials for intravenous administration. It is commonly supplied in concentrations of 5 mg/mL.
Contraindications: Isoxsuprine Injection is contraindicated in patients with known hypersensitivity to isoxsuprine or any component of the formulation. It should not be used in individuals with acute hemorrhage, cerebral hemorrhage, coronary artery disease, or severe arterial bleeding.
Warnings and Precautions: Use caution when administering Isoxsuprine Injection to patients with a history of cardiovascular disease, as it may exacerbate certain conditions such as angina or myocardial infarction. Monitor patients closely for signs of adverse reactions, including tachycardia, hypotension, or arrhythmias. Discontinue use if significant adverse effects occur.
Adverse Reactions/Side Effects: Common adverse reactions associated with Isoxsuprine Injection include palpitations, tachycardia, headache, dizziness, nausea, and flushing. Less frequently, it may cause hypotension, arrhythmias, or allergic reactions such as rash or urticaria.
Drug Interactions: Isoxsuprine Injection may interact with other medications that affect blood pressure or heart rate, such as beta-blockers, calcium channel blockers, or antiarrhythmic agents. Concurrent use with these drugs may potentiate or antagonize the effects of isoxsuprine.
Use In Specific Populations Description: Safety and efficacy of Isoxsuprine Injection in pediatric patients, pregnant women, and nursing mothers have not been established. Use caution and consult with a healthcare professional before administering to individuals in these populations.
How Supplied/Storage and Handling: Isoxsuprine Injection is supplied as a sterile solution in vials for intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.
