Imipramine Injection
- Packing: 2 Ml Vial
- Available Strength : 12.5 Mg/Ml
Description
Product Description: Imipramine Injection is a sterile solution containing the active ingredient imipramine hydrochloride, a tricyclic antidepressant. It is used for the treatment of depression, enuresis (bedwetting), and other psychiatric disorders.
Indications and Usage: Imipramine Injection is indicated for the treatment of depression in adults and adolescents, enuresis (bedwetting) in children, and other psychiatric disorders such as anxiety disorders and obsessive-compulsive disorder (OCD).
Dosage and Administration: The dosage of Imipramine Injection depends on the patient's age, weight, and the severity of the condition being treated. It is typically administered by intramuscular or intravenous injection. The recommended dosage usually ranges from 75 to 150 mg per day for depression and 25 to 75 mg per day for enuresis, divided into multiple doses.
Dosage Forms and Strengths: Imipramine Injection is available as a sterile solution in vials or ampules for intramuscular or intravenous administration. Each milliliter of the solution typically contains a specified amount of imipramine hydrochloride, typically expressed in milligrams per milliliter (mg/mL).
Contraindications: Imipramine Injection is contraindicated in patients with a known hypersensitivity to imipramine or any component of the formulation. It should not be used in patients with acute or recent myocardial infarction, glaucoma, or urinary retention.
Warnings and Precautions: Use caution when administering Imipramine Injection to patients with a history of cardiovascular disorders, seizures, or liver impairment. Monitor patients closely for signs of worsening symptoms, including suicidal ideation, behavioral changes, and serotonin syndrome. Adjust the dosage as necessary based on the patient's clinical response and tolerance.
Adverse Reactions/Side Effects: Common adverse reactions associated with Imipramine Injection may include dry mouth, constipation, blurred vision, dizziness, drowsiness, and weight gain. Rare but serious adverse reactions may include cardiac arrhythmias, seizures, and serotonin syndrome.
Drug Interactions: Imipramine Injection may interact with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and anticholinergic agents. Concurrent use may potentiate or antagonize the effects of imipramine, leading to increased or decreased efficacy or adverse reactions. Use caution and monitor patients closely for signs of drug interactions.
Use In Specific Populations Description: Safety and efficacy of Imipramine Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Imipramine Injection is supplied as a sterile solution in vials or ampules for intramuscular or intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.