Hyoscine Butyl Bromide Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 20Mg/Ml
Description
Product Description: Hyoscine Butyl Bromide Injection is a pharmaceutical formulation containing hyoscine butyl bromide, a muscarinic antagonist with antispasmodic properties. It is indicated for the treatment of gastrointestinal and genitourinary smooth muscle spasms, including those associated with irritable bowel syndrome, renal colic, and biliary colic. This injection provides rapid relief from spasmodic pain and discomfort by blocking the action of acetylcholine on muscarinic receptors in smooth muscle.
Indications and Usage: Hyoscine Butyl Bromide Injection is indicated for the symptomatic relief of smooth muscle spasms in the gastrointestinal and genitourinary tracts. It is used to alleviate abdominal pain and discomfort associated with conditions such as irritable bowel syndrome, renal colic, biliary colic, and urinary tract spasm. Additionally, it may be used as an adjunctive therapy in diagnostic and therapeutic procedures involving these organ systems.
Dosage and Administration: The dosage of Hyoscine Butyl Bromide Injection varies depending on the patient's age, weight, and the severity of symptoms. It is administered via intravenous or intramuscular route under the supervision of a healthcare professional. The dosage regimen should be individualized based on the patient's response to therapy and any underlying medical conditions.
Dosage Forms and Strengths: Hyoscine Butyl Bromide Injection is available as a sterile solution in single-dose vials. Each mL of solution contains hyoscine butyl bromide equivalent to 20 mg of hyoscine base.
Contraindications: Hyoscine Butyl Bromide Injection is contraindicated in patients with known hypersensitivity to hyoscine butyl bromide or any of the excipients. It should not be used in patients with glaucoma, obstructive uropathy, obstructive gastrointestinal conditions, or myasthenia gravis.
Warnings and Precautions: Caution should be exercised when administering Hyoscine Butyl Bromide Injection to patients with autonomic neuropathy, tachycardia, or prostatic hypertrophy, as it may exacerbate these conditions. It should be used with caution in elderly patients, as they may be more susceptible to anticholinergic effects such as urinary retention or constipation.
Adverse Reactions/Side Effects: Common adverse reactions associated with Hyoscine Butyl Bromide Injection include dry mouth, blurred vision, dizziness, and urinary retention. Rare but serious adverse reactions may include tachycardia, palpitations, or allergic reactions such as rash or pruritus. If any adverse reactions occur, the infusion should be discontinued, and appropriate medical treatment initiated.
Drug Interactions: Hyoscine Butyl Bromide Injection may potentiate the effects of other anticholinergic agents or medications with antimuscarinic activity, such as tricyclic antidepressants or antipsychotic drugs. Concurrent use with drugs that cause central nervous system depression, such as opioids or benzodiazepines, may increase the risk of drowsiness or respiratory depression. Close monitoring is recommended when administering hyoscine with other medications affecting the autonomic nervous system.
Use In Specific Populations Description: The safety and efficacy of Hyoscine Butyl Bromide Injection in pediatric patients, geriatric patients, and pregnant or lactating women have not been established. Use with caution in these populations, and only if the potential benefits outweigh the risks. Close monitoring is recommended in patients with renal or hepatic impairment.
How Supplied/Storage and Handling: Hyoscine Butyl Bromide Injection is supplied as a sterile solution in single-dose vials. It should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F), protected from light and moisture. Do not freeze. Discard any unused portion of the solution.