Folic Acid Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 15 Mg/Ml
Description
Product Description: Folic Acid Injection is a sterile solution containing synthetic folic acid, a water-soluble B vitamin essential for various cellular functions, including DNA synthesis, red blood cell formation, and tissue growth. It is indicated for the treatment and prevention of folic acid deficiency, which can lead to megaloblastic anemia, neural tube defects, and other complications. Folic Acid Injection is available for intramuscular or intravenous administration.
Indications and Usage: Folic Acid Injection is indicated for the treatment of folic acid deficiency, including megaloblastic anemia due to folic acid deficiency, as well as for the prevention of neural tube defects in pregnant women. It is also used in patients with malabsorption syndromes or other medical conditions that impair folic acid absorption.
Dosage and Administration: The dosage of Folic Acid Injection depends on the patient's clinical condition, severity of deficiency, and individualized treatment goals. It is typically administered by intramuscular or intravenous injection. The recommended dosage for adults with folic acid deficiency is usually 1 mg injected intramuscularly or intravenously once daily for up to 10 days, followed by maintenance therapy with 0.1 to 0.5 mg daily.
Dosage Forms and Strengths: Folic Acid Injection is available as a sterile solution in vials or ampules containing specific concentrations of folic acid. Each mL of the injection contains a defined amount of folic acid, allowing for accurate dosing and therapeutic efficacy.
Contraindications: Folic Acid Injection is contraindicated in patients with known hypersensitivity to folic acid or any of the excipients. It should not be used in patients with untreated pernicious anemia or other vitamin B12 deficiency without concomitant administration of vitamin B12.
Warnings and Precautions: Patients with megaloblastic anemia should be evaluated for vitamin B12 deficiency before initiating folic acid therapy, as concurrent treatment with vitamin B12 may be necessary to prevent neurological complications. Folic Acid Injection should be used with caution in patients with renal impairment, as high doses may exacerbate pre-existing renal dysfunction.
Adverse Reactions/Side Effects: Adverse reactions associated with Folic Acid Injection are rare but may include hypersensitivity reactions, injection site reactions, and gastrointestinal disturbances. High doses of folic acid may mask symptoms of vitamin B12 deficiency, leading to neurological complications if not adequately treated.
Drug Interactions: Folic Acid Injection may interact with certain medications, including antiepileptic drugs, methotrexate, and sulfasalazine, leading to decreased folic acid levels or impaired absorption. Patients taking these medications may require supplementation with folic acid to prevent deficiency.
Use In Specific Populations Description: Safety and efficacy of Folic Acid Injection in pregnant or nursing women, pediatric patients, and elderly patients have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Folic Acid Injection is supplied as a sterile solution in vials or ampules for intramuscular or intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.