Famotidine Injection
- Packing: 2 Ml Ampoule.
- Available Strength : 10 Mg/Ml
Description
Product Description: Famotidine Injection is a sterile, intravenous solution containing the histamine-2 (H2) receptor antagonist famotidine. It is used for the treatment and prevention of various gastrointestinal conditions, including duodenal ulcers, gastric ulcers, gastroesophageal reflux disease (GERD), and pathological hypersecretory conditions such as Zollinger-Ellison syndrome.
Indications and Usage: Famotidine Injection is indicated for the short-term treatment of active duodenal ulcers, active benign gastric ulcers, and symptomatic GERD. It is also used for the maintenance therapy for duodenal ulcer patients after healing and for the treatment of pathological hypersecretory conditions.
Dosage and Administration: The recommended dosage of Famotidine Injection depends on the indication and severity of the condition being treated. It is administered intravenously over a specific duration determined by the healthcare provider, typically ranging from 15 minutes to 2 hours.
Dosage Forms and Strengths: Famotidine Injection is available as a sterile solution in single-dose vials. The concentration of famotidine in the solution is typically 20 mg/2 mL or 40 mg/5 mL per vial.
Contraindications: Famotidine Injection is contraindicated in patients with known hypersensitivity to famotidine or any component of the formulation. It should not be co-administered with drugs that require gastric pH for absorption, such as atazanavir and delavirdine.
Warnings and Precautions: Before administering Famotidine Injection, healthcare providers should evaluate patients for risk factors associated with gastric malignancy, C. difficile-associated diarrhea, and acute porphyria. Long-term use may increase the risk of pneumonia and Clostridium difficile-associated diarrhea.
Adverse Reactions/Side Effects: Common adverse reactions associated with Famotidine Injection include headache, diarrhea, constipation, and abdominal pain. Other potential side effects may include thrombocytopenia, agranulocytosis, and hypersensitivity reactions.
Drug Interactions: Famotidine Injection may interact with certain medications, including procainamide, warfarin, and triazolam. Concomitant use with drugs that require acidic pH for absorption may reduce their efficacy. Healthcare providers should carefully evaluate patients for potential drug interactions before administering Famotidine Injection.
Use In Specific Populations Description: Famotidine Injection is generally considered safe for use in pregnant and lactating women, although caution should be exercised, especially during the first trimester of pregnancy. It should be used with caution in pediatric patients, particularly those younger than 1 month old, due to limited safety data in this population.
How Supplied/Storage and Handling: Famotidine Injection is supplied as a sterile solution in single-dose vials. It should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F), protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.