Ethinyloestradiol Tablets

Description

Product Description: Ethinyloestradiol Tablets are a synthetic form of estrogen used in hormone replacement therapy (HRT) and oral contraceptives. They contain ethinylestradiol, which is structurally similar to the natural hormone estradiol. These tablets are formulated to regulate hormonal imbalances and prevent pregnancy when used in combination with progestin.

Indications and Usage: Ethinyloestradiol Tablets are indicated for the treatment of menopausal symptoms, such as hot flashes, vaginal dryness, and osteoporosis prevention. Additionally, they are widely used in oral contraceptives to prevent pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the endometrium.

Dosage and Administration: The dosage of Ethinyloestradiol Tablets varies depending on the indication and the specific formulation. For menopausal symptoms, typical dosages range from 0.5 to 2 mg daily. In oral contraceptives, ethinylestradiol is often combined with progestin, and the recommended dosage regimen is usually one tablet daily for 21 days followed by a 7-day break without tablets.

Dosage Forms and Strengths: Ethinyloestradiol Tablets are available in various strengths, typically ranging from 0.01 mg to 0.05 mg per tablet. They are supplied in blister packs or bottles containing a specified number of tablets.

Contraindications: Ethinyloestradiol Tablets are contraindicated in patients with a history of estrogen-dependent tumors, thromboembolic disorders, liver dysfunction, and undiagnosed abnormal genital bleeding. They should also not be used during pregnancy or lactation.

Warnings and Precautions: Patients taking Ethinyloestradiol Tablets should be monitored closely for potential adverse effects, including an increased risk of cardiovascular events, venous thromboembolism, stroke, and breast cancer. Regular medical check-ups and mammograms may be recommended. Caution should be exercised in patients with a history of hormone-sensitive cancers, liver dysfunction, or gallbladder disease.

Adverse Reactions/Side Effects: Common adverse reactions associated with Ethinyloestradiol Tablets may include breast tenderness, nausea, headache, vaginal bleeding or spotting, and fluid retention. Serious adverse effects such as cardiovascular events, thromboembolism, and gallbladder disease are rare but require prompt medical attention.

Drug Interactions: Ethinyloestradiol Tablets may interact with certain medications, including rifampicin, barbiturates, phenytoin, and St. John's Wort, potentially reducing their efficacy or increasing the risk of adverse effects. Patients should inform their healthcare provider of all medications they are taking before starting Ethinyloestradiol therapy.

Use In Specific Populations Description: Ethinyloestradiol Tablets are intended for use in women experiencing menopausal symptoms or seeking contraception. They should be used with caution in patients with a history of estrogen-dependent tumors, cardiovascular disease, or liver dysfunction.

How Supplied/Storage and Handling: Ethinyloestradiol Tablets are supplied in blister packs or bottles containing a specified number of tablets. They should be stored at room temperature (20°C to 25°C) away from moisture and heat. Unused tablets should be properly disposed of according to local regulations.