Estradiol Valerate Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 10 Mg/Ml
Description
Product Description: Estradiol Valerate Injection is a medication containing estradiol valerate, a synthetic estrogen hormone. It is formulated for intramuscular injection and is used for hormone replacement therapy.
Indications and Usage: Estradiol Valerate Injection is indicated for the treatment of menopausal symptoms such as hot flashes, vaginal dryness, and mood swings. It is also used to prevent osteoporosis and to regulate menstrual cycles in women with hormonal imbalances.
Dosage and Administration: The dosage of Estradiol Valerate Injection depends on the individual patient's hormonal needs and response to therapy. It is typically administered intramuscularly once every 1 to 4 weeks. The dose may vary depending on the severity of symptoms and the patient's age and medical history.
Dosage Forms and Strengths: Estradiol Valerate Injection is available as a clear, colorless solution in vials or ampules. Each milliliter of solution contains a specified amount of estradiol valerate, typically ranging from 10 mg to 20 mg per mL.
Contraindications: Estradiol Valerate Injection is contraindicated in patients with a history of breast cancer, endometrial cancer, or other hormone-sensitive malignancies. It should not be used in pregnant women or individuals with a known hypersensitivity to any of the components of the formulation.
Warnings and Precautions: Before initiating therapy with Estradiol Valerate Injection, healthcare providers should evaluate patients for the presence of cardiovascular disease, thromboembolic disorders, liver dysfunction, and other conditions that may be exacerbated by hormone therapy. Patients should be monitored regularly for signs of estrogen-related adverse effects, including breast tenderness, fluid retention, and changes in mood.
Adverse Reactions/Side Effects: Common adverse reactions associated with Estradiol Valerate Injection include nausea, headache, breast pain, breakthrough bleeding, and changes in menstrual flow. Other potential side effects may include weight gain, bloating, mood swings, and allergic reactions.
Drug Interactions: Estradiol Valerate Injection may interact with other medications, including anticoagulants, corticosteroids, anticonvulsants, and certain herbal supplements. Healthcare providers should carefully monitor patients receiving concomitant therapy for potential drug interactions.
Use In Specific Populations Description: Estradiol Valerate Injection is not recommended for use in pregnant women due to the risk of fetal harm. It should be used with caution in women with a history of breast or endometrial cancer, as estrogen therapy may increase the risk of tumor recurrence.
How Supplied/Storage and Handling: Estradiol Valerate Injection is supplied as a solution in vials or ampules. It should be stored at controlled room temperature, protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.
