Doxapram Injection
- Packing: 5 Ml Vial
- Available Strength : 20 Mg/Ml
Description
Product Description: Doxapram Injection is a meticulously formulated pharmaceutical solution designed to stimulate respiratory function in patients with respiratory depression. It contains doxapram hydrochloride, a respiratory stimulant known for its ability to increase tidal volume and respiratory rate. Manufactured to the highest quality standards, this injection offers vital support for patients experiencing respiratory depression due to various causes.
Indications and Usage: Doxapram Injection is indicated for the short-term treatment of respiratory depression associated with conditions such as drug overdose, post-anesthesia recovery, and neuromuscular disorders. It is used to stimulate breathing in patients with inadequate respiratory effort or depressed respiratory drive to prevent hypoxia and respiratory failure.
Dosage and Administration: The dosage of Doxapram Injection varies depending on the severity of respiratory depression and the patient's response to therapy. It is typically administered via intravenous infusion or intramuscular injection under the supervision of a qualified healthcare professional. The initial dose may range from 0.5 to 1 mg/kg, with subsequent doses adjusted based on clinical response.
Dosage Forms and Strengths: Doxapram Injection is available as a sterile solution in vials containing specific concentrations of doxapram hydrochloride formulated for parenteral administration. Each vial is carefully manufactured to ensure accurate dosing and optimal therapeutic outcomes.
Contraindications: This product is contraindicated in patients with a known hypersensitivity to doxapram hydrochloride or any of the excipients. It should not be used in patients with epilepsy or a history of seizures, as doxapram may lower the seizure threshold. Additionally, it is contraindicated in patients with acute respiratory failure due to chronic obstructive pulmonary disease (COPD).
Warnings and Precautions: Healthcare providers should monitor patients receiving Doxapram Injection closely for signs of respiratory distress, arrhythmias, and hypertension. Rapid infusion rates should be avoided to minimize the risk of adverse effects such as hypertension and tachycardia. Caution should be exercised when administering to patients with cardiovascular disease or hypertension.
Adverse Reactions/Side Effects: Common adverse reactions associated with Doxapram Injection include tachycardia, hypertension, and tremors. Nausea, vomiting, and headache may also occur. Less common adverse effects include arrhythmias, respiratory depression, and allergic reactions. Patients should be advised to report any unusual symptoms promptly.
Drug Interactions: Concomitant use of Doxapram Injection with other drugs that affect cardiovascular function or respiratory drive may potentiate the effects of doxapram or alter its pharmacokinetics. Healthcare providers should review the patient's medication profile carefully to avoid potential drug interactions.
Use In Specific Populations Description: Safety and efficacy of Doxapram Injection in pediatric patients, pregnant women, and nursing mothers have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Doxapram Injection is supplied as a sterile solution in vials for parenteral administration. It should be stored at controlled room temperature away from light and moisture. Care should be taken to avoid freezing or excessive heat exposure. Unused portions should be discarded according to standard procedures for biohazardous waste.