Dimenhydrinate Injection
- Packing: 1 Ml Ampoule, 5 Ml Vial
- Available Strength : 50 Mg/Ml
Description
Product Description: Dimenhydrinate Injection is a sterile solution containing dimenhydrinate, a medication used to prevent and treat motion sickness and nausea. Dimenhydrinate is an antihistamine with antiemetic properties. It works by blocking the action of histamine in the brain, thereby alleviating symptoms of motion sickness and nausea. This injectable formulation provides a rapid onset of action and is suitable for patients who cannot take oral medications.
Indications and Usage: Dimenhydrinate Injection is indicated for the prevention and treatment of motion sickness and nausea associated with various conditions, including travel, vertigo, and postoperative recovery. It is commonly used in emergency departments, surgical settings, and ambulatory care clinics to provide rapid relief of symptoms.
Dosage and Administration: The dosage of Dimenhydrinate Injection depends on the patient's age, weight, and medical condition, as well as the severity of symptoms. It is administered intramuscularly or intravenously. The recommended dosage for adults is typically 50 to 100 mg every 4 to 6 hours as needed, not exceeding 400 mg in 24 hours. Pediatric dosages should be adjusted based on age and weight.
Dosage Forms and Strengths: Dimenhydrinate Injection is available as a sterile solution in vials or ampules for parenteral administration. Each mL of solution contains 50 mg of dimenhydrinate. It is supplied in various packaging sizes to accommodate different clinical settings and patient needs.
Contraindications: Dimenhydrinate Injection is contraindicated in patients with a known hypersensitivity to dimenhydrinate or any component of the formulation. It should not be used in patients with narrow-angle glaucoma, urinary retention, severe liver disease, or respiratory depression. Use caution in patients with asthma, chronic obstructive pulmonary disease (COPD), or hyperthyroidism.
Warnings and Precautions: Use caution when administering Dimenhydrinate Injection to elderly patients, as they may be more sensitive to the sedative effects of the medication. Avoid concurrent use with other central nervous system depressants, such as alcohol, opioids, or benzodiazepines, as this may increase the risk of respiratory depression and sedation. Monitor patients for signs of anticholinergic effects, including dry mouth, constipation, and urinary retention.
Adverse Reactions/Side Effects: Common adverse reactions associated with Dimenhydrinate Injection include drowsiness, dizziness, blurred vision, dry mouth, and constipation. Less common side effects may include urinary retention, tachycardia, and confusion. Severe adverse reactions, such as seizures or allergic reactions, are rare but may occur.
Drug Interactions: Dimenhydrinate Injection may interact with other medications that have sedative effects, such as opioids, benzodiazepines, and antipsychotics. Concurrent use may potentiate central nervous system depression and increase the risk of respiratory depression and sedation. Avoid concurrent use with monoamine oxidase inhibitors (MAOIs) due to the risk of hypertensive crisis.
Use In Specific Populations Description: Safety and efficacy of Dimenhydrinate Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Dimenhydrinate Injection is supplied as a sterile solution in vials or ampules for parenteral administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.
