Cyanocobalamin Injection
- Packing: 1 Ml, 2 Ml, 5 Ml, 10 Ml Vial
- Available Strength : 500 Mcg/Ml, 1000 mcg/ml
Description
Product Description: Cyanocobalamin Injection is a sterile solution containing cyanocobalamin, a synthetic form of vitamin B12. It is essential for the formation of red blood cells, neurological function, and DNA synthesis. Cyanocobalamin Injection is indicated for the treatment and prevention of vitamin B12 deficiency, which can lead to anemia and neurological disorders. It is available for intramuscular or intravenous administration.
Indications and Usage: Cyanocobalamin Injection is indicated for the treatment of vitamin B12 deficiency, including pernicious anemia, nutritional deficiency, and malabsorption syndromes. It is also used for the prevention of vitamin B12 deficiency in individuals with inadequate dietary intake, gastrointestinal disorders, or other medical conditions that impair absorption.
Dosage and Administration: The dosage of Cyanocobalamin Injection depends on the severity of the deficiency and the patient's clinical response. It is typically administered by intramuscular injection into the deltoid or gluteal muscle. The recommended dosage for adults with vitamin B12 deficiency is usually 1000 mcg injected intramuscularly once daily for one week, followed by 1000 mcg injected intramuscularly once a week for four weeks, and then 1000 mcg injected intramuscularly once a month thereafter.
Dosage Forms and Strengths: Cyanocobalamin Injection is available as a sterile solution in vials or ampules containing specific concentrations of cyanocobalamin. Each mL of the injection contains a defined amount of cyanocobalamin, allowing for accurate dosing and therapeutic efficacy.
Contraindications: Cyanocobalamin Injection is contraindicated in patients with known hypersensitivity to cyanocobalamin or any of the excipients. It should not be used in patients with Leber's disease (hereditary optic nerve atrophy) or cobalt hypersensitivity.
Warnings and Precautions: Patients with megaloblastic anemia should be evaluated for folic acid deficiency before initiating cyanocobalamin therapy, as concurrent treatment with folic acid may be necessary to prevent neurological complications. Cyanocobalamin should be used with caution in patients with renal impairment, as high doses may exacerbate pre-existing renal dysfunction.
Adverse Reactions/Side Effects: Adverse reactions associated with Cyanocobalamin Injection are rare but may include hypersensitivity reactions, injection site reactions, and transient hypokalemia. High doses of cyanocobalamin may cause transient acne-like rash and transient symptoms of diarrhea and itching.
Drug Interactions: Cyanocobalamin may interact with certain medications, including metformin, proton pump inhibitors, and H2-receptor antagonists, leading to decreased absorption of vitamin B12. Patients taking these medications may require supplementation with vitamin B12 to prevent deficiency.
Use In Specific Populations Description: Safety and efficacy of Cyanocobalamin Injection in pregnant or nursing women, pediatric patients, and elderly patients have not been established conclusively. Healthcare providers should assess the potential risks and benefits before prescribing this medication in these populations.
How Supplied/Storage and Handling: Cyanocobalamin Injection is supplied as a sterile solution in vials or ampules for intramuscular or intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.