Bupivacaine Injection
- Packing: 4 ml Ampoule, 10ml, 20 ml Vial
- Available Strength : 5 Mg/Ml
Description
Product Description: Bupivacaine Injection is a sterile solution containing bupivacaine, a local anesthetic agent belonging to the amide group. It is used for regional anesthesia, nerve block, and pain management. Bupivacaine works by blocking nerve impulses, thereby producing reversible loss of sensation in a specific area of the body. It is available in various concentrations for use in different clinical settings.
Indications and Usage: Bupivacaine Injection is indicated for local or regional anesthesia for surgery, obstetrics, and acute pain management. It is commonly used for epidural, spinal, and peripheral nerve blocks, as well as for infiltration anesthesia in surgical procedures and postoperative pain control.
Dosage and Administration: The dosage of Bupivacaine Injection varies depending on the type and duration of anesthesia required, the patient's age, weight, and medical condition, as well as the surgical procedure being performed. It is administered by infiltration, nerve block, epidural, or spinal injection techniques. The dosage should be individualized to achieve optimal anesthesia while minimizing systemic toxicity.
Dosage Forms and Strengths: Bupivacaine Injection is available in multiple concentrations, ranging from 0.125% to 0.75%, depending on the intended use and clinical requirements. It is supplied as a clear, colorless solution in vials or ampules for parenteral administration.
Contraindications: Bupivacaine Injection is contraindicated in patients with a known hypersensitivity to bupivacaine or any component of the formulation. It should not be used for obstetrical anesthesia, including epidural anesthesia for cesarean section, because of the risk of severe maternal and fetal adverse reactions.
Warnings and Precautions: Use caution when administering Bupivacaine Injection to patients with impaired cardiac conduction, severe liver disease, or severe renal impairment, as they may be at increased risk of systemic toxicity. Accidental intravascular injection may result in serious adverse effects, including cardiac arrest, respiratory depression, and neurological deficits.
Adverse Reactions/Side Effects: Common adverse reactions associated with Bupivacaine Injection include hypotension, bradycardia, nausea, vomiting, dizziness, headache, and injection site reactions. Rare but serious adverse effects may include cardiac arrhythmias, seizures, respiratory depression, and neurological complications.
Drug Interactions: Bupivacaine Injection may interact with other medications that affect cardiac conduction or central nervous system function, such as beta-blockers, calcium channel blockers, and opioids. Concurrent use of these drugs may increase the risk of adverse effects, including cardiac toxicity and respiratory depression.
Use In Specific Populations Description: Safety and efficacy of Bupivacaine Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Bupivacaine Injection is supplied as a sterile solution in vials or ampules for parenteral administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.