Bupivacaine + Dextrose Injection
- Packing: 4 Ml Ampoule.
- Available Strength : 5 Mg + 80 Mg
Description
Product Description: Bupivacaine + Dextrose Injection is a sterile solution containing bupivacaine hydrochloride, a long-acting local anesthetic, and dextrose, a type of sugar. This combination is used for regional anesthesia and pain management. Bupivacaine provides local anesthesia by blocking nerve impulses, while dextrose serves as a vehicle for administration and may also provide some analgesic effect. It is available in various concentrations for different clinical applications.
Indications and Usage: Bupivacaine + Dextrose Injection is indicated for local or regional anesthesia for surgery, obstetrics, and acute pain management. It is commonly used for epidural, spinal, and peripheral nerve blocks, as well as for infiltration anesthesia in surgical procedures and postoperative pain control.
Dosage and Administration: The dosage of Bupivacaine + Dextrose Injection varies depending on the type and duration of anesthesia required, the patient's age, weight, and medical condition, as well as the surgical procedure being performed. It is administered by infiltration, nerve block, epidural, or spinal injection techniques. The dosage should be individualized to achieve optimal anesthesia while minimizing systemic toxicity.
Dosage Forms and Strengths: Bupivacaine + Dextrose Injection is available in multiple concentrations, ranging from low to high concentrations of bupivacaine and dextrose, depending on the intended use and clinical requirements. It is supplied as a clear, colorless solution in vials or ampules for parenteral administration.
Contraindications: Bupivacaine + Dextrose Injection is contraindicated in patients with a known hypersensitivity to bupivacaine, dextrose, or any component of the formulation. It should not be used for obstetrical anesthesia, including epidural anesthesia for cesarean section, because of the risk of severe maternal and fetal adverse reactions.
Warnings and Precautions: Use caution when administering Bupivacaine + Dextrose Injection to patients with impaired cardiac conduction, severe liver disease, or severe renal impairment, as they may be at increased risk of systemic toxicity. Accidental intravascular injection may result in serious adverse effects, including cardiac arrest, respiratory depression, and neurological deficits.
Adverse Reactions/Side Effects: Common adverse reactions associated with Bupivacaine + Dextrose Injection include hypotension, bradycardia, nausea, vomiting, dizziness, headache, and injection site reactions. Rare but serious adverse effects may include cardiac arrhythmias, seizures, respiratory depression, and neurological complications.
Drug Interactions: Bupivacaine + Dextrose Injection may interact with other medications that affect cardiac conduction or central nervous system function, such as beta-blockers, calcium channel blockers, and opioids. Concurrent use of these drugs may increase the risk of adverse effects, including cardiac toxicity and respiratory depression.
Use In Specific Populations Description: Safety and efficacy of Bupivacaine + Dextrose Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Bupivacaine + Dextrose Injection is supplied as a sterile solution in vials or ampules for parenteral administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.