Artesunate Injection

Description

Product Description: Artesunate Injection is a vital medication used in the treatment of severe malaria caused by Plasmodium falciparum. It belongs to the artemisinin class of antimalarial drugs and is highly effective in rapidly reducing parasite load, thereby saving lives in cases of severe malaria.

Indications and Usage: Artesunate Injection is indicated for the treatment of severe malaria caused by Plasmodium falciparum. It is recommended by the World Health Organization (WHO) as the first-line treatment for severe malaria in endemic regions.

Dosage and Administration: Dosage and administration of Artesunate Injection should be as per the guidelines provided by healthcare authorities or healthcare professionals. It is usually administered intravenously or intramuscularly, with dosages adjusted based on the severity of the infection and the patient's weight.

Dosage Forms and Strengths: Artesunate Injection is available as a sterile solution in vials containing various strengths, typically ranging from 60 mg to 240 mg per vial.

Contraindications: Artesunate Injection is contraindicated in patients with known hypersensitivity to artemisinin derivatives or any component of the formulation.

Warnings and Precautions: Artesunate Injection should be administered under the supervision of a healthcare professional experienced in the management of severe malaria. Close monitoring of vital signs and laboratory parameters is essential during treatment. Patients with a history of cardiac disorders or other significant comorbidities may require special attention.

Adverse Reactions/Side Effects: Common adverse reactions associated with Artesunate Injection include transient neutropenia, anemia, and elevation of liver enzymes. Rare but severe adverse effects such as allergic reactions, hemolysis, and delayed hemolysis may occur.

Drug Interactions: There are no known significant drug interactions with Artesunate Injection. However, caution should be exercised when administering concurrently with other medications metabolized by the cytochrome P450 system.

Use In Specific Populations Description: Artesunate Injection is generally considered safe for use in pregnant women, particularly in cases of severe malaria where the benefits outweigh the risks. It is excreted in breast milk; however, the risk to the nursing infant is considered low compared to the risk of untreated severe malaria. Safety and efficacy in pediatric patients have been established, with dosage adjustments based on weight.

How Supplied/Storage and Handling: Artesunate Injection is supplied as a sterile solution in single-dose vials. It should be stored at controlled room temperature (20°C to 25°C) and protected from light. Do not freeze. Discard any unused portion of the solution.