Amoxycillin + Sulbactam Injection

Description

Product Description: Amoxicillin + Sulbactam Injection is a combination antibiotic medication used for the treatment of bacterial infections. It combines the antibiotic amoxicillin with the beta-lactamase inhibitor sulbactam to enhance its efficacy against a broader range of bacteria.

Indications and Usage: Amoxicillin + Sulbactam Injection is indicated for the treatment of infections caused by susceptible strains of bacteria. Common infections treated include respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections.

Dosage and Administration: The dosage of Amoxicillin + Sulbactam Injection depends on the severity of the infection, the patient's weight, and renal function. It is typically administered intravenously at a dose determined by the prescribing healthcare provider based on the specific infection being treated.

Dosage Forms and Strengths: Amoxicillin + Sulbactam Injection is available as a sterile solution in vials containing a fixed ratio of amoxicillin to sulbactam. Common strengths include 1 gram/0.5 gram per vial or 2 grams/1 gram per vial.

Contraindications: Amoxicillin + Sulbactam Injection is contraindicated in patients with a known hypersensitivity to penicillins, cephalosporins, or sulbactam. It should not be used in patients with a history of severe allergic reactions to these medications.

Warnings and Precautions:

• Hypersensitivity reactions, including severe allergic reactions such as anaphylaxis, may occur with the use of Amoxicillin + Sulbactam Injection. Patients should be monitored closely for signs of allergic reactions during therapy.
• Prolonged use of antibiotics may result in the overgrowth of nonsusceptible organisms, including fungi. Monitor patients for signs of superinfection during therapy.
• Use caution in patients with renal impairment, as dosage adjustment may be necessary.

Adverse Reactions/Side Effects: Common adverse reactions associated with Amoxicillin + Sulbactam Injection include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. Hypersensitivity reactions, including rash, pruritus, and urticaria, may also occur.

Drug Interactions: Amoxicillin + Sulbactam Injection may interact with other medications, including oral contraceptives and anticoagulants. Use caution when administering concomitant medications and monitor for potential drug interactions.

Use In Specific Populations Description: Safety and efficacy of Amoxicillin + Sulbactam Injection in pediatric patients, pregnant women, and nursing mothers have not been established. Use in these populations should be carefully considered, and the potential risks and benefits should be weighed.

How Supplied/Storage and Handling: Amoxicillin + Sulbactam Injection is supplied as a sterile solution in single-dose vials. It should be stored at controlled room temperature (20°C to 25°C) and protected from light. Reconstituted solutions should be used within the recommended time frame and stored according to instructions.