Aminophylline Injection
- Packing: 10 Ml Ampoule.
- Available Strength : 25 Mg/Ml
Description
Product Description: Aminophylline Injection is a sterile solution containing the active ingredient aminophylline, a bronchodilator belonging to the methylxanthine class of drugs. It is used for the treatment of reversible airway obstruction associated with conditions such as asthma, chronic bronchitis, and emphysema.
Indications and Usage: Aminophylline Injection is indicated for the treatment of bronchospasm associated with reversible airway obstruction, including asthma, chronic bronchitis, and emphysema. It acts as a bronchodilator, relaxing smooth muscles in the airways and improving airflow to the lungs.
Dosage and Administration: The dosage of Aminophylline Injection depends on the patient's age, weight, and the severity of the condition being treated. It is typically administered by intravenous infusion at a rate determined by the healthcare provider. The recommended dosage usually ranges from 0.4 to 0.8 mg/kg per hour, with adjustments made based on clinical response and serum theophylline levels.
Dosage Forms and Strengths: Aminophylline Injection is available as a sterile solution in vials or ampules for intravenous administration. Each milliliter of the solution typically contains a specified amount of aminophylline, typically expressed in milligrams per milliliter (mg/mL).
Contraindications: Aminophylline Injection is contraindicated in patients with a known hypersensitivity to aminophylline, theophylline, or any component of the formulation. It should not be used in patients with acute myocardial infarction, severe hypotension, or uncontrolled arrhythmias.
Warnings and Precautions: Use caution when administering Aminophylline Injection to patients with underlying cardiovascular disorders, hypertension, or seizure disorders. Monitor patients closely for signs of worsening symptoms, including palpitations, arrhythmias, seizures, and hypotension. Adjust the dosage as necessary based on the patient's clinical response and serum theophylline levels.
Adverse Reactions/Side Effects: Common adverse reactions associated with Aminophylline Injection may include nausea, vomiting, headache, insomnia, palpitations, and tremors. Rare but serious adverse reactions may include cardiac arrhythmias, seizures, and allergic reactions such as rash or anaphylaxis.
Drug Interactions: Aminophylline Injection may interact with certain medications, including beta-blockers, corticosteroids, and sympathomimetic agents. Concurrent use may potentiate or antagonize the effects of aminophylline, leading to increased or decreased bronchodilation. Adjust the dosage of concomitant medications as necessary and monitor patients closely for signs of drug interactions.
Use In Specific Populations Description: Safety and efficacy of Aminophylline Injection in pediatric patients, elderly patients, pregnant women, and nursing mothers have not been established conclusively. Use caution and individualize the dosage and administration based on the patient's age, weight, and medical condition.
How Supplied/Storage and Handling: Aminophylline Injection is supplied as a sterile solution in vials or ampules for intravenous administration. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.