Propranolol Injection
- Packing: 1 Ml Ampoule.
- Available Strength : 1 Mg/Ml
Description
Product Description: Propranolol Injection is a sterile, non-pyrogenic solution used for intravenous administration. It is a beta-adrenergic blocking agent indicated for the treatment of hypertension, angina pectoris, myocardial infarction, cardiac arrhythmias, and other cardiovascular conditions.
Indications and Usage: Propranolol Injection is indicated for the management of hypertension, angina pectoris, and tachyarrhythmias. It is also used for the prophylaxis of myocardial infarction, migraine headaches, and essential tremor.
Dosage and Administration: The dosage of Propranolol Injection should be individualized based on the patient's condition and response to therapy. It is administered intravenously at an initial rate of 1 mg/min, titrated upward as needed to achieve the desired therapeutic effect. The maximum recommended dose is 2 mg/min.
Dosage Forms and Strengths: Propranolol Injection is available as a sterile solution in vials or ampules for intravenous use. It is commonly supplied in concentrations of 1 mg/mL or 2 mg/mL.
Contraindications: Propranolol Injection is contraindicated in patients with bronchial asthma, severe bradycardia, heart block greater than first degree, cardiogenic shock, and overt cardiac failure. It should not be used in patients with a known hypersensitivity to propranolol or other beta-blockers.
Warnings and Precautions: Use caution when administering Propranolol Injection to patients with diabetes mellitus, hyperthyroidism, or peripheral vascular disease. Abrupt withdrawal of beta-blockers may precipitate rebound hypertension or angina.
Adverse Reactions/Side Effects: Adverse reactions associated with Propranolol Injection may include bradycardia, hypotension, bronchospasm, dizziness, fatigue, and depression. Rarely, hepatotoxicity, agranulocytosis, or thrombocytopenia may occur.
Drug Interactions: Propranolol Injection may interact with other medications that affect cardiac conduction or blood pressure, such as calcium channel blockers, antiarrhythmics, or antihypertensive agents. Concurrent use with monoamine oxidase inhibitors (MAOIs) may result in hypertensive crisis.
Use In Specific Populations Description: Safety and efficacy of Propranolol Injection in pediatric patients, pregnant women, and nursing mothers have not been established. Use caution and consult with a healthcare professional before administering to individuals in these populations.
How Supplied/Storage and Handling: Propranolol Injection is supplied as a sterile solution in vials or ampules for intravenous use. It should be stored at controlled room temperature (20°C to 25°C) away from light and moisture. Care should be taken to ensure proper storage and handling to maintain the integrity of the product. Unused portions should be discarded according to standard procedures for biohazardous waste.