Isoflupredone Acetate Injection Suspension
- Packing: 5 Ml, 10 Ml, 30 Ml Vial
- Available Strength : 2 Mg/Ml
Description
Product Description: Isoflupredone Acetate Injection Suspension is a sterile injectable formulation containing isoflupredone acetate, a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. It is formulated as a suspension for intramuscular or intra-articular administration.
Indications and Usage: Isoflupredone Acetate Injection Suspension is indicated for the treatment of inflammatory conditions where corticosteroid therapy is appropriate. It is commonly used in the management of arthritis, synovitis, tendonitis, bursitis, and other inflammatory disorders affecting the musculoskeletal system.
Dosage and Administration: The dosage of Isoflupredone Acetate Injection Suspension varies depending on the severity of the condition being treated, the patient's response to therapy, and the route of administration. It is typically administered by intramuscular injection at a dosage ranging from 0.25 to 4 mg/kg body weight. For intra-articular administration, the dosage is typically 1 to 2 mg per affected joint.
Dosage Forms and Strengths: Isoflupredone Acetate Injection Suspension is available as a sterile suspension in vials. The suspension is typically supplied in concentrations ranging from 10 mg/mL to 50 mg/mL.
Contraindications: Isoflupredone Acetate Injection Suspension is contraindicated in patients with known hypersensitivity to corticosteroids or any component of the formulation. It is also contraindicated in patients with systemic fungal infections, untreated bacterial infections, and viral infections affecting the skin or mucous membranes.
Warnings and Precautions: Before initiating treatment with Isoflupredone Acetate Injection Suspension, healthcare providers should assess patients for contraindications and preexisting conditions, including diabetes, hypertension, osteoporosis, and peptic ulcer disease. Prolonged use may increase the risk of adrenal suppression, Cushing's syndrome, and opportunistic infections.
Adverse Reactions/Side Effects: Common adverse reactions associated with Isoflupredone Acetate Injection Suspension include local pain or discomfort at the injection site, transient leukopenia, and fluid retention. Other potential side effects may include gastrointestinal disturbances, mood changes, and increased susceptibility to infections.
Drug Interactions: Isoflupredone Acetate Injection Suspension may interact with certain medications, including anticoagulants, antidiabetic agents, and immunosuppressants. Concomitant use with other corticosteroids or NSAIDs may increase the risk of gastrointestinal ulceration and bleeding.
Use In Specific Populations Description: Isoflupredone Acetate Injection Suspension should be used with caution in pregnant and lactating women, as corticosteroids may cross the placenta and enter breast milk. It is not recommended for use in pediatric patients, as safety and efficacy have not been established in this population.
How Supplied/Storage and Handling: Isoflupredone Acetate Injection Suspension is supplied as a sterile suspension in vials. It should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F), protected from light and moisture. Unused portions should be discarded according to local regulations for biohazardous waste disposal.